The Center for Southern Studies in the Social Sciences and the Humanities was an interdisciplinary center established in 1965 in order to help "organize and systematize existing scholarly interest" in Southern Studies at Duke and elsewhere. Past chairs include Edgar T. Thompson and Thomas H. Naylor. The Center folded in the late 1970s. Collection contains materials pertaining to operation and activities of the Center for Southern Studies in the Social Studies and the Humanities including correspondence, minutes, manuscripts, printed matter, clippings, and other materials. Materials range in date from 1961-1969, with the bulk dates of 1965-1967.

Collection contains materials pertaining to operation and activities of the Center for Southern Studies in the Social Studies and the Humanities including correspondence, minutes, manuscripts, printed matter, clippings, and other materials, with the bulk dates of 1965-1967. In 1966, the Center sponsored an inaugural symposium, "The Changing South: An Agenda for Research." Approximately half of the material present consists of correspondence and copies of the papers that were presented at the symposium. Materials range in date from 1961-1969, with the bulk dates of 1965-1967.