Collection chiefly consists of photostatic copies of correspondence written by and to Benjamin Waterhouse, and brings together material from various U. S. collections. The copies seem to have been made in the 1940s. Includes some original letters acquired by Duke University. The bulk of the material, correspondence by and to Waterhouse, and minutes of meetings of the Corporation of Harvard College, relates to vaccination and other medical practice, and Waterhouse's removal from his Harvard professorship. Correspondents include: John Warren, J.C. Warren, James Jackson, John Gorham, William Jenks, John Redman Coxe, Benjamin Lincoln, Samuel Williams, James Sullivan, Benjamin Silliman, John Redman, William Cogswell, John Lathrop, James Monroe, J. T. Kirkland, Henry Dearborn, Henry Alexander Scammell Dearborn, James Winthrop, Thomas Jefferson, Daniel Webster, Jared Sparks, Lewis Cass, and Romeo Elton. Collection also includes photostatic copy of Waterhouse's 1794 journal describing a trip to Saratoga Springs. Materials arranged chronologically.
Transcriptions of some of the original correspondence are present. Forms part of the Trent Manuscripts Collection and was acquired as part of the History of Medicine Collections at Duke University.