This series contains Bassett's correspondence as well as miscellaneous ephemera and personal materials from his medical training and career. Some of the correspondence predates Bassett, but the majority of it relates to his work as a bacteriologist and health officer in the Savannah Health Department; his efforts to research medical history and biographical data for the Georgia Medical Society; and his participation in various medical and public health professional organizations in the early twentieth century. Additional materials relating specifically to the Savannah Health Department and the Georgia Medical Society are held in those series.

This series includes project files, reports, statistics, and publications related to Bassett's work as a bacteriologist, physician, and health officer for Savannah and its surrounding county, Chatham County. Some of the initiatives represented are vaccination; clean water; milk safety and inspections; infant/child health; prenatal healthcare; maternal healthcare; and Bassett's role in training for medical students, nurses, and midwives. This series also includes a selection of Bassett's reports on mortality and disease for the city of Savannah, divided by race.