The LGBT Task Force makes ongoing assessments of attitudes and conditions throughout the University regarding gay, lesbian, bisexual, and transgender persons and issues. Records include minutes, agenda, correspondence, reports, printed email, clippings, printed matter, and other records of the Task Force.

Records include minutes, agenda, correspondence, reports, printed email, clippings, printed matter, and other records of the Task Force. Topics covered by the materials include University policies on same-sex marriages and benefits, surveys administered to students on sexuality and transgender issues, the creation and funding of the Center for LGBT Life (now the Center for Gender and Sexual Diversity), and many other subjects.

The Vice President of Student Affairs oversees the Division of Student Affairs, involved in all aspects of student life at Duke University. William J. Griffith was Dean of Student Affairs and then Vice President of Student Affairs from 1963-1991. The Vice President for Student Affairs Records include correspondence, reports, memorandums, and other materials related to the operations of the Division of Student Affairs and cover such topics as student organizations, student housing, student government, student activities, administrative planning around student facilities and resources, and many other subjects.

The collection includes a wide variety of materials related to the operations of the Student Affairs office. Much of the collection is correspondence, with many reports, printed materials, and memorandums, as well as other materials.

Topics include student organizations and activities, including student government, fraternities, student living groups, interest groups, and publications; administrative activities and policies focused on student life and well-being, including student housing, student health and insurance, resources for supporting student life, and facilities for students; administrative and campus activities including arts and cultural activities such as the Duke Players, Chapel activities and services, and the Publications Board; and events of significance to the Duke community, including materials related to the Allen Building Takeover, protests and demonstrations, and many other topics.

An addition (Accession UA2018-0084) contains correspondence and subject files from Larry Moneta, VP of Student Affairs. An addition (Accession UA2020-0050) consists of email correspondence transferred from Moneta's email account. Email originals are in Outlook PST format, with a copy migrated to MBOX. Accession UA2022-0030 contains materials related to Duke Student Health.

Some materials were removed April 2007 and now make up the Office of Student Affairs Reference Collection.