The prints and negatives include images of men, women, and children with cases of syphilis, and a few images of x-rays of body parts, what appear to be microsope views of cells, and aerial images of one or more towns in Syria. Images of people focus on areas of the body with significant lesions, growths, or other obvious symptoms of syphilis. The images are grouped into envelopes within each folder, and most correspond to images featured in Hudson's monograph, with labeling on the envelopes indicating the figure number used in the book. Some of these images include the original envelopes in which they were apparently mailed to Ellis Hudson, which may have handwritten notes that include the name, age, and gender of the person in the image, as well as some information about their medical history. Many of the original images were cropped to focus on the symptomatic area, and envelopes may include the cropped or uncropped print, or both. The faces of people depicted in the images may appear in the original image.