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The Center for Civic Engagement, currently Duke Civic Engagement, opened in 2007 as part of DukeEngage. Duke Civic Engagement coordinates and supports civic engagement activities across campus and within communities. The collection consists of reports such as the Civic Engagement inventory, Duke Civic Action Plan, and Engaging Excellence: A Report Concerning Civic Engagement at Duke University as well as promotional materials for events.

The Duke Climate Coalition is a student-run organization founded in 2015. The group focuses on educating Duke's community on climate change and advocating for environmentally sensitive policies and business practices at Duke. The collection consists of research materials, project planning materials, photographs and records related to the organizations fossil fuel divestment campaign.

The Duke Coffeehouse is a student-run coffee shop and performance venue located on East Campus near Wilson Dorm. The collection includes log books of accounts and shows, tally sheets for cash registers, flyers for the Brickside Music Festival, stickers, and other materials related to the business of the Coffeehouse.

The Duke Disability Alliance is a student organization dedicated to making Duke more inclusive and accessible. The Duke Disability Alliance Records include materials from a 2017 exhibit for Disability Pride Week on NeuroDIVERSITY and Inclusion, created by students in a Writing 101 class, as well as the DDA's blog. Also includes a digital copy of the (In)Visible:COVID-19 at Duke booklet with audio descriptions.

The Duke-Durham Neighborhood Partnership(DDNP) collaborates with the twelve communities surrounding the Duke Campus on a wide range of neighborhood support and revitalization projects.The Duke-Durham Neighborhood Partnership Records contains planning documents, correspondence, meeting notes and other materials on the programs and initiatives sponsored by the Duke Durham Neighborhood Partnership between 2000 and 2012. It also includes materials pertaining to the administrative management of civic affairs and community outreach efforts at Duke University.

The Duke Endowment was established by James Buchanan Duke as a perpetual charitable trust in 1924, with the following types of beneficiaries, mainly residing in North Carolina and South Carolina: non-profit hospitals and child care institutions; educational institutions; and rural churches of the Conference of the Methodist Episcopal Church, South (now the United Methodist Church). The Duke Endowment Archives span the years 1902 to 2006, with the bulk of the material dating from 1925 through 2006. The collection documents the administration of the corpus of the trust and the charitable contributions made to the categories of recipients named in the Indenture and Deed of Trust establishing The Endowment. The majority of the records are arranged into series that reflect the organization of the institution, including the Board of Trustees, Treasurer's Office, Controller's Office, Investment Office, Education Division and Committee on Communications, Health Care and Child Care Divisions, and Rural Church Division. Smaller series, documenting such other activities as record-keeping, publications, and history of The Endowment, include: Central Files, Oral History Project, Trust Under Will, Publications, Miscellaneous, Photographic Materials, and Audiovisual Materials. The collection consists of the following types of materials: correspondence; minutes of meetings; financial records; applications for assistance from hospitals, child care institutions, and churches; statistics; publications; oral history tapes and transcripts; architectural drawings and blueprints; photographs; audio cassettes; and miscellaneous records and papers. The geographic focus is primarily North Carolina and South Carolina.

J.B. Duke acquired a lot on the northeast corner of Fifth Avenue and 78th Street and commissioned Horace Trumbauer to draw the plans for a new residence in 1909. It was in this mansion that his daughter Doris was born and raised. After J.B.'s death in 1925, Nanaline continued to live in the mansion until January, 1958 when she and Doris donated the house to New York University's Institute of Fine Arts. Throughout her adulthood Doris continued to live in New York City, residing in a penthouse located at 3 E. 84th Street and a penthouse at 475 Park Avenue, which was her last New York City residence when she died in 1993. The collection primarily documents the expenses and daily operations of running and maintaining three large residences in New York City. Materials include invoices and receipts for repairs and renovations to the residences, correspondence and memoranda relating to routine matters of the residences including expenses, inventories of furniture, fixtures, and other household items, and appraisals of the residences and their household effects. A majority of the architectural records in this collection are related to the design and construction of J.B. Duke's mansion at 1 E. 78th Street.

James Buchanan (J.B.) Duke (1856-1925) was known for his business acumen, especially in national and international tobacco industries and hydroelectric power. He was married twice, first to Lillian McCredy, who he divorced in 1906 and then Nanaline Holt Inman, who was his spouse from 1907 until his death in 1925. This collection primarily documents James B. Duke's business and personal activities. Materials include business and personal correspondence, invoices and receipts for both business and personal purchases, financial and legal reports, the last will and testaments of both James B. and Nanaline Duke, and materials documenting the divorce proceedings of J.B. and Lillian McCredy Duke. Miscellaneous records include a booklet tracing the Duke family geneaology.

Duke Farms, a 2,700 acre estate located in Hillsborough, New Jersey, was developed by James Buchanan (J.B.) Duke beginning in 1893. After J.B. Duke's death in 1925, Doris Duke inherited the property. Over the course of nearly seven decades she worked to continue the legacy of Duke Farms and introduced environmentally-friendly and innovative farming methods into the operations of Duke Farms and purchased and restored farms and farmstead structures in order to forestall the rapid loss of farmland to urban development. When she died she left the majority of her estate to the Doris Duke Charitable Foundation with her expressed wish that Duke Farms be used to drive positive change on a number of key issues regarding the stewardship of the natural environment. The collection is arranged into four series: Administrative Records, Duke Business Office Records, Duke Farms Main Residence Records, and Architectural Records. It spans the years 1859 to 2004, beginning with the early vision and evolution of the estate by James Buchanan (J.B.) Duke, the enhancement and management of the estate by Doris Duke after she inherited control of it upon her father's death, and ending with the general upkeep of the estate after Doris Duke's death in 1993. The collection primarily documents the daily operations of running, renovating, and maintaining the Duke Farms estate, and includes daily activity reports, correspondence, notes, and specifications for various architectural projects at Duke Farms, invoices and vouchers for repairs at different buildings on the estate, cattle inventories and cow registrations, financial ledgers and cashbooks, and security ledgers and reports. The architectural records are further arranged into seven sub series and contain a wide assortment of records, including blueprints, diazo prints, site plans, schedules, and maps. The materials document a variety of design, construction, and farm-related activities at Duke Farms.