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Jenner sends some grafts for Davies' use. He makes recommendations for treatment of headaches, then comments on his bad tenant, Cole. Date has been added in red ink

Jenner notes that he has seen George Hopkins, whose epileptic fits have rendered him incapable of serving as a lawyer.

Jenner asks for more information about an incident regarding his wall along the Severn River. He goes on to describe wife Catherine's illness and how she longs for the bouquets Davies used to send her. He urges Davies to record the state of vegetation. He notes that Stephen Jenner is recovering.

Jenner consults on the treatment of Mrs. Cox, a patient. Includes prescriptions, a tonic, and recommendations for application of leeches.

Jenner discusses lagging legislation in Dublin regarding smallpox inoculation and practices elsewhere. Includes envelope.

Jenner consults on two cases, John Hickes, who has a brain injury, and an unnamed woman from Elberton, who has an "intestinal derangement."

Jenner inquires regarding a report he has heard that Fewster has been threatened with destruction. In a postscript, Jenner writes a note regarding their patient in Tytherington.

Jenner describes the papers he is sending to his Royal Highness regarding vaccination practices around the globe.

Jenner comments on the rain, then suggests the trade of a tongue for a sparerib. He promises to send books as soon as young Willy learns to read.

Jenner states that he is sorry to learn William has been ill, then invites him to dine on venison that afternoon.