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Rush notes that the fever has increased more in one week than it had in three weeks in 1793 and 1797. He had made plans to leave in 7-10 days when the U. S. Mint was closed, but by the end of the letter announces more immediate plans to remove to Sydenham, which has been prepared for the family and servants. Their son John is arriving via his ship in New Castle. A note was appended to the letter in 1848, saying that the close of the letter was cut out for an autograph seeker.

Rush notes that John arrived, and they are now at Sydenham. He also reports that he has sold the Chapel farm for $2,500. He describes a new remedy he has developed for yellow fever. The signature has been excised from this letter.

Rush points out that though staying in the country helps him forget all that is going on around him, he cannot forget the poor, sick, and dying in the city. Three more persons were admitted to the hospital this day than were admitted in 1793.

Rush notes that his pupil is better, and that he is using profuse sweating as part of his treatment for the fever. A later note was appended to the letter stating that Mrs. Rush allowed the signature to be cut away for an autograph.

Rush reports that despite being exposed to the fever daily for two months, he is still healthy. However, he has "felt, mourned, and wept" until he could no longer do so. He reports that poor people chase him down in the street, and that he carries medicine with him in order to do all he can to help them. Free blacks and servants form a large percentage of his patients.

Rush recounts all the improvements he has made for her at Sydenham. He will begin sending the family from town with the warm weather in May or June.

Rush comments on commerce and the work of physicians, and on Philadelphia physicians opposed to use of mercury and bloodletting.

Rush writes a brief note to inform Julia that a friend has failed, physically.

Rush writes that deaths from fever are decreasing, and he will soon end his engagement with city hospital. He outlines activities in the family, and their preparations for her return the following week. The signature to this letter has been excised.

Rush makes treatment recommendations for an undisclosed ailment.

Rush records the benefits of using Kinepox over variolation to inoculate against smallpox.

Rush thanks Dr. Bostock for his essay on respiration, saying he will read it with interest and awaits Bostock's future work on the topic. The rest of the letter relates to Rush's English ancestry and friendship with Bostock's father.

Copy of a letter Rush composed to Jefferson regarding appointments Jefferson has made, as well as the impact of yellow fever epidemics on commerce with Europe.

Rush thanks Bostock for his article "Analysis of Animal Fluides," then provides requested anecdotes regarding Bostock's father. Rush comments upon treatment for pulmonary consumption and the use of bloodletting in parturition and pregnancy.

Rush outlines how the family spent July 4th for Julia, then discusses possible successors to University of Pennsylvania chemist, James Woodhouse. Letter includes a poem by William Rush to his mother.

Rush describes his parting with their son, James, and announces that Dr. Coxe has been appointed Professor of Chemistry. Includes a letter from Samuel Rush to his mother.

Rush relates how he misses Julia, then describes the activities of their boys. He notes that the weather has been uncommonly cool, which has damaged crops. There has also been an outbreak of yellow fever in the city, but he expects it to be checked by the cool weather. He points out that the "ejection of Mr. Erskine's convention with our government by the British Court" has caused outrage in the city.

Rush writes regarding a Mr. Carter's debts, particularly regarding his coffin and grave.

Rush writes a more detailed letter regarding Mr. Carter's debts and ill treatment of Carter, who was insane, by his family. Includes a statement of charges certified by the hospital's steward. Letter features an additional written comment made by Henderson or someone in his firm.

Rush replies to a requested consult regarding a severe case of hemorrhoids or other bowel problem. He proposes that if the patient is willing to visit Philadelphia, the problem can be treated surgically.

Rush congratulates Jones on his decision to leave Congress, and records his own regrets regarding public service, with particular regard to the funding system and the banks. He now believes American citizens "unfit for and undeserving of liberty."

Rush writes his memories of John Rodgers, the patriarch of Presbyterianism in the United States. Rodger's had been his boyhood friend at Dr. Finley's school in Maryland. In 1777, Rush had taken care of Rodger's son in Kingston following a battle.

Rush writes an unsolicited recommendation for Dr. James Mease to serve as head of the Office of Purveyor for the army's medical department.

Rush's draft letter acknowledges receipt of his certificate of membership in the Royal Academy of Medicine in Madrid, and laments the general lack of appreciation one experiences at the end of a career.

Rush's copy of a letter to Hosack on the origin of the fortifications and other Native ruins in different parts of the country.

Rush's copy of a letter assuring the Baron he has read all of the medical segments of Van Sach's letters from Surinam, regarding the origins of infectious disease, including yellow fever and influenza. He commends Van Sach on his plans for preventing fevers in Surinam.

Rush's copy of a letter he wrote regarding his memories of Dr. William Cullen.

The diary records Rush's travel, accompanied by a servant and via horses, between the outskirts of Philadelphia and Carlisle, Pennsylvania, for an initial meeting with the trustees of Dickinson College. During the meeting the Trustees selected Dr. Charles Nisbet to serve as the College's first president. Rush described the taverns and other travel lodges at which he stopped, along with Tavern staff and other patrons, the quality of the food and drink, along with conversations he witnessed or took part in. Discussion often centered on the topics of the Constitution, paper money, as well as Dickinson College. Rush also described the results of a rapid Spring thaw on the Susquehanna River, the unusually cold weather, the scenery, and the presence whiskey stills in Irish settlements and their impact on their communities.

In the casebook, Rush provided brief histories for his treatment of about 75 individuals. Entries generally included the year, patient's name, presented medical issue, dates of treatment, prescriptions applied, pulses noted, and the progression or resolution of the problem. Rheumatism was the most common complaint, along with dropsy (edema), pneumonia, diarrhea, and mania. Among the other illnesses listed were palsy (paralysis), fever, typhus, epilepsy, consumption, scurvy, hydrothorax, swelled spleen, and hysteria.

Lecture or essay regarding use of cordial remedies and bleeding, a discussion of influenza, along with a 2-page partial report on an autopsy that noted the presence of a tumor in the abdomen.

Contains primarily Benjamin Rush's records of his expenses, including tax and bond payments, rental property fees, classes and dance lessons for family members, as well as money lent or advanced, accounts paid, cash received, and income from boarders. Rush noted the wide variety of areas where his money was spent, from postage and travel, to clothing and shoes, to household provisions and stores, along with medicines purchased. In addition, Rush created accounts for servants when they arrived, and noted their wages and any increased wages, advances, or loans; cloth, clothing, and shoes provided; with occasional notes on their personal and work habits and work history, and when they exited his service or married. Several of the comments have been redacted, along with a few pages of the account book. Finally, Rush made a few brief commonplace notes randomly in the volume, providing a "style sheet" for description of pulses, outlining a few prescriptions for patients, describing the weather, listing inventories of his furniture and linens, recording a few recipes, and in 1783, noting the news of possible peace with England.

Rush issued this certificate documenting that Samuel Cole attended 3 courses of his lectures on Chemistry and Pharmacy. Signed by Rush, Professor of Chemistry, College of Philadelphia.

Sworn statement that the certificate dated 1 July 1784, payable to Thomas Gilby and signed by John Pierce, is really the property of Dickinson College. signed by Benjamin Rush.

Land deed for the Williamsburg tract purchased by Benjamin Rush, signed by Gov. Thomas Mifflin and Dep. Sec. James Trimble, with the Pennsylvania State seal, with notice that it was recorded in the state patent books.