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The Frederick Fraser Papers comprises documents of a cotton planter in South Carolina. Papers include correspondence concerning the sale of cotton, some personal correspondence, assorted financial transactions concerning cotton, some miscellaneous personal papers, and a scrapbook that contains a variety of materials related to social life in South Carolina and the Civil War, including: correspondence, newspaper clippings, poems, copies of tombstone engravings, invitations, photographs, and postcards.

Collection assembled by Lisa Unger Baskin containing printed ephemera, receipts, manuscripts, handbills, catalogs, decorative trade cards, prospectuses, circulars, political campaign materials, and other advertisements from the United Kingdom, Western Europe, and the United States. The bulk of the collection's materials advertise businesses or services offered by women, including millinery, fancy goods, hair work, tea, painting, teaching, music, bricklaying, gardening, dressmaking, apothecaries, and a clairvoyant. Also includes calling cards and bookplates with women's names, and assorted ephemera relating to women's pay, income, or work, including a pensioner's card for a firefighter's widow and a pamphlet about life insurance for women.

The Picture File was created and maintained beginning in the 1950s by the Duke University Manuscript Department staff and its institutional successors as a vertical file of pictorial works separated from manuscript collections as well as acquired individually. The collection is large and diverse, with images dating from the 18th through the 20th centuries. Engravings feature prominently, with photographs a close second. The predominant genre is portraits of political and military leaders, authors, artists, physicians, scientists, and others. Members of the Duke family and others from Durham, N.C. are also present. In the Socialist Party Series there are numerous images of leader Eugene Debs. Topics range widely, with a focus on American history, including the Revolutionary and Civil Wars; history and culture of the southern U.S.; and U.S. and European politics. A significant number of individuals in the People Series are African Americans, ranging from individual studio portraits to groups of individuals and racist caricatures and cartoons; a smaller number are of Native Americans.

Materials from the branch of the Hypes family that descended from Henry Hypes of Xenia, Ohio: Samuel Henry Hypes (1826-1917); his son, William Findlay Hypes; his grandson, Samuel Loomis Hypes; and his great-grandson, William P. Hypes. Collection includes a wide range of material from the Hypes family, particularly William Findlay Hypes, Samuel Loomis Hypes, and William P. Hypes. William Findlay Hypes' materials highlight his career at Marshall Fields and Co. of Chicago and his service as President of the Y.M.C.A. of Chicago, with emphasis on his family's world tour on behalf of the Y.M.C.A. in 1924-1925. Hundreds of postcards and photographs collected by the family are contained in the papers, including images from India, Ceylon (Sri Lanka), China, Europe, Egypt, and many more places, most unlabeled. Some material from Samuel Loomis Hypes' army service during World War I is also included, the most noteworthy being 24 black and white photographs featuring crowds awaiting the signing of the Treaty of Versailles and the shipping of troops back to the United States, including photographs of African American soldiers. Materials from William P. Hypes relate to his work with the Y.M.C.A. in the mid-twentieth century. The family's research into their genealogy and family history, unidentified family photographs, and smaller amounts of correspondence and material from other family members are also included.

Rector of Langley Burrell, Wiltshire, England; Nonjuror. Volume of writings and correspondence of Thomas Stampe, who, in 1701, recanted an oath of allegiance to William and Mary, and thus became a Nonjuror while a beneficed clergy of the Church of England. Writings and letters all relate to the issues of religion, government, and allegiances, and mention George Hickes and Thomas Ken, Bishop of Bath and Wells. Also includes correspondence with Gilbert Burnet, the Bishop of Salisbury.

Cosimo III de' Medici was the penultimate Medici Grand Duke of Tuscany. He reigned from 1670 to 1723, and was the elder son of Grand Duke Ferdinando II. Collection contains a letter on vellum that is a notice from Cosimo III de Medici (Duke of Etruria etc.), to John Philip de Incontris of Florence regarding rents of 222 and 220L in reference to John Philip’s equestrian military preparation. Dated at Florence, 1 February 1705, in the 35th year of the Dukedom of Etruria.